RESEARCH ARTICLE Fluoxetine modulates brea

the brain in a murine mod cy n ry events remains high. Brain metastasis represents a par-ticularly challenging complication of breast cancer. It is reduced ability of therapeutic agents to cross the blood– brain barrier (BBB) [5]. In fact, many of the newest and Shapovalov et al. BMC Cancer 2014, 14:598 http://www.biomedcentral.com/1471-2407/14/598brain metastases by investigating possible effects of2Department of Biomedical Engineering, University of Rochester, Box 270168