Tudor staphylococcal nuclease (Tudor-SN) and Argonaute (Ago) are conserved compo-nents of the basic RNA interference (RNAi) machinery with a variety of functions including immune response and gene regulation. The RNAi machinery has been characterized in tick vectors of human and animal diseases but information is not available on the role of Tudor-SN in tick RNAi and other cellular processes. Our hypothesis is that tick Tudor-SN is part of the RNAi machinery and may be involved in innate immune response and other cellular pro-cesses. To address this hypothesis, Ixodes scapularis and I. ricinus ticks and/or cell lines were used to annotate and characterize the role of Tudor-SN in dsRNA-mediated RNAi, immune response to infection with the ric...
Abstract Background Progress in generating comprehensive EST libraries and genome sequencing is sett...
Background: There has been an emergence and expansion of tick-borne diseases in Europe, Asia and Nor...
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacter...
Tudor staphylococcal nuclease (Tudor-SN) and Argonaute (Ago) are conserved components of the basic R...
Tudor staphylococcal nuclease (Tudor-SN) and Argonaute (Ago) are conserved components of the basic R...
Contribution: Performed the experiments and Analyzed the dataInternational audienceTudor staphylococ...
This is an open access article distributed under the terms of the Creative Commons Attribution Licen...
Arboviruses are transmitted by distantly related arthropod vectors such as mosquitoes (class In-sect...
Ribonucleases play important roles in the RNA interference (RNAi) pathway. The Dicer endonuclease co...
<p>(A) Differential expression/representation of Tudor-SN and Ago genes/proteins in <i>I</i>. <i>sca...
Arboviruses are transmitted by distantly related arthropod vectors such as mosquitoes (class Insecta...
Ticks are an example of an efficient ectoparasite that feeds on a variety of hosts including humans,...
BACKGROUND: Ixodid ticks are important vectors of a wide variety of viral, bacterial and protozoan p...
<p>(A) <i>Tudor-SN</i> mRNA levels were analyzed using RNA extracted from <i>I</i>. <i>scapularis</i...
Ticks are efficient vectors of arboviruses, although less than 10% of tick species are known to be v...
Abstract Background Progress in generating comprehensive EST libraries and genome sequencing is sett...
Background: There has been an emergence and expansion of tick-borne diseases in Europe, Asia and Nor...
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacter...
Tudor staphylococcal nuclease (Tudor-SN) and Argonaute (Ago) are conserved components of the basic R...
Tudor staphylococcal nuclease (Tudor-SN) and Argonaute (Ago) are conserved components of the basic R...
Contribution: Performed the experiments and Analyzed the dataInternational audienceTudor staphylococ...
This is an open access article distributed under the terms of the Creative Commons Attribution Licen...
Arboviruses are transmitted by distantly related arthropod vectors such as mosquitoes (class In-sect...
Ribonucleases play important roles in the RNA interference (RNAi) pathway. The Dicer endonuclease co...
<p>(A) Differential expression/representation of Tudor-SN and Ago genes/proteins in <i>I</i>. <i>sca...
Arboviruses are transmitted by distantly related arthropod vectors such as mosquitoes (class Insecta...
Ticks are an example of an efficient ectoparasite that feeds on a variety of hosts including humans,...
BACKGROUND: Ixodid ticks are important vectors of a wide variety of viral, bacterial and protozoan p...
<p>(A) <i>Tudor-SN</i> mRNA levels were analyzed using RNA extracted from <i>I</i>. <i>scapularis</i...
Ticks are efficient vectors of arboviruses, although less than 10% of tick species are known to be v...
Abstract Background Progress in generating comprehensive EST libraries and genome sequencing is sett...
Background: There has been an emergence and expansion of tick-borne diseases in Europe, Asia and Nor...
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacter...