Editorial Phage Display Informatics

Copyright © 2013 Jian Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Phage display is an efficient laboratory technique that can be used to screen for specific peptides and proteins displayed on the surface of bacteriophage. Since Professor George Smith of the University of Missouri pioneered the powerful and flexible method in 1980s [1], it has been adapted and improved bymany scientists fromvarious fields. For example, the sequence displayed on the coat proteins of phage has been extended from random peptides to protein fragments, enzymes, antibodies, and even the whole peptidome of a given species [2]; the way of panning has been expanded from in vitro to in vivo [3]; the platform for screening has been extended fromplates and beads tomicrofluidic devices [4]. In addition to the development of “hardwares ” of phage display