POSTER PRESENTATION Open Access An information theoretic measure of cross- frequency coupling

The coupling of neuronal oscillations between cortical areas has been proposed both as a mechanism for top-down and bottom-up signaling in the brain. These inter-actions may facilitate the coordination of both local and distributed networks across different time scales. How-ever, we are still exploring what the best method is to quantify them. Of particular interest has been the role of phase-amplitude cross-frequency coupling (CFC), and a variety of methods to analyze this have been proposed [1]. Thus far none of these stands out as an ideal mea-sure. We propose the use of Mutual Information to quantify CFC. We test the performance of this metho