Regression

and progression of microalbuminuria in adolescents with childhood onset diabetes mellitus Original article Purpose: Although microalbuminuria is considered as an early marker of nephropathy in diabetic adults, available information in diabetic adolescents is limited. The aim of this study was to investigate prevalence and frequency of regression of microalbuminuria in type 1 (T1DM) and type 2 diabetes mellitus (T2DM) patients with childhood onset. Methods: One hundred and nine adolescents (median, 18.9 years; interquartile range (IQR), 16.5–21.0 years) with T1DM and 18 T2DM adolescents (median, 17.9 years; IQR, 16.8–18.4 years) with repeated measurements of microalbuminuria (first morning urine microalbumin/creatinine ratios) were included. The median duration of diabetes was 10.1 (7.8–14.0) years and 5.0 (3.5–5.6) years, respectively, and follow-up period ranged 0.5–7.0 years. Growth parameters, estimated glomerular filtration rate, glycosylated hemoglobin (HbA1c) and lipid profiles were obtaine