UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainl
Base moieties in DNA are spontaneously threatened by naturally occurring chemical reactions such as ...
Although genomic DNA is predominantly duplex under physiological conditions, particular sequence mot...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2016.Ca...
Cytotoxicity of 5-fluorouracil (FU) and 5-fluoro-2′-deoxyuridine (FdUrd) due to DNA fragmentation du...
5-fluorouracil (5-FU) is a widely used anticancer drug thatdisruptspyrimidinenucleotidepool balances...
Recent evidence indicates that 5-fluorouracil (5-FlUra) is incor- to remove 5-FlUra. In particular, ...
5-Fluorouracil (5-FU), a chemotherapeutic drug commonly used in cancer treatment, imbalances nucleot...
Contains the introduction. The papers are not included for copyright reasons.DNA is susceptible to c...
Cellular DNA repair is a frontline system that is responsible for maintaining genome integrity and t...
5-Fluorouracil (5-FU), a chemotherapeutic drug commonly used in cancer treatment, imbalances nucleot...
Cancer is a deadly manifestation of diseases in which abnormal cells undergo uncontrolled proliferat...
-ethenocytosine (εC). The εA and εC residues are highly mutagenic in mammalian cells and eliminated ...
Our current understanding of cancer suggests that every tumour has individual features. Approaches t...
Base excision repair (BER), responsible for the removal of altered DNA bases, is accomplished via tw...
International audienceDNA repair is implemented through a large variety of mechanisms, each of them ...
Base moieties in DNA are spontaneously threatened by naturally occurring chemical reactions such as ...
Although genomic DNA is predominantly duplex under physiological conditions, particular sequence mot...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2016.Ca...
Cytotoxicity of 5-fluorouracil (FU) and 5-fluoro-2′-deoxyuridine (FdUrd) due to DNA fragmentation du...
5-fluorouracil (5-FU) is a widely used anticancer drug thatdisruptspyrimidinenucleotidepool balances...
Recent evidence indicates that 5-fluorouracil (5-FlUra) is incor- to remove 5-FlUra. In particular, ...
5-Fluorouracil (5-FU), a chemotherapeutic drug commonly used in cancer treatment, imbalances nucleot...
Contains the introduction. The papers are not included for copyright reasons.DNA is susceptible to c...
Cellular DNA repair is a frontline system that is responsible for maintaining genome integrity and t...
5-Fluorouracil (5-FU), a chemotherapeutic drug commonly used in cancer treatment, imbalances nucleot...
Cancer is a deadly manifestation of diseases in which abnormal cells undergo uncontrolled proliferat...
-ethenocytosine (εC). The εA and εC residues are highly mutagenic in mammalian cells and eliminated ...
Our current understanding of cancer suggests that every tumour has individual features. Approaches t...
Base excision repair (BER), responsible for the removal of altered DNA bases, is accomplished via tw...
International audienceDNA repair is implemented through a large variety of mechanisms, each of them ...
Base moieties in DNA are spontaneously threatened by naturally occurring chemical reactions such as ...
Although genomic DNA is predominantly duplex under physiological conditions, particular sequence mot...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2016.Ca...