Add to ORKGBackground The aim of this study was to compare the performance of several recently developed assays for the detection of multi- and extensively drug-resistant tuberculosis (M/XDR-TB) in a large, multinational field trial. Methods Samples from 1,128 M/XDR-TB suspects were examined by Line Probe Assay (LPA), Pyro-sequencing (PSQ), and Microscopic Observation of Drug Susceptibility (MODS) and com-pared to the BACTECMGIT960 reference standard to detect M/XDR-TB directly from patient sputum samples collected at TB clinics in India, Moldova, and South Africa. Results Specificity for all three assays was excellent: 97–100 % for isoniazid (INH), rifampin (RIF), moxifloxacin (MOX) and ofloxacin (OFX) and 99–100 % for amikacin (AMK), capreomycin (CA...
Journal Article; Research Support, Non-U.S. Gov't;BACKGROUND Nucleic acid amplification tests are i...
INTRODUCTION:Despite recent diagnostic advances, the majority of multidrug-resistant tuberculosis (M...
Objective: Tuberculosis is an important public health problem in developed and, especially, developi...
<div><p>Background</p><p>The aim of this study was to compare the performance of several recently de...
BackgroundThe aim of this study was to compare the performance of several recently developed assays ...
Pulmonary tuberculosis still remains a major communicable disease worldwide. In 2013, 9 million peop...
Performance evaluation of three commercial molecular assays for the detection of Mycobacterium tuber...
Background: The Xpert MTB/RIF assay has garnered significant interest as a sensitive and rapid diagn...
Background The Xpert1MTB/RIF (Xpert) is an automated molecular test for simultaneous detection of tu...
Background In India as elsewhere, multi-drug resistance (MDR) poses a serious challenge in the contr...
to multidrug-resistant tuberculosis diagnosis and treatment initiation: a qualitative comparison of ...
Background: An algorithm instituted following Xpert MTB/RIF (Xpert) introduction in South Africa adv...
commercial assays for the detection of Mycobacterium tuberculosis complex (MTBC), Xpert MTB/RIF (Cep...
Background Xpert MTB/RIF (Xpert) was piloted in Kazakhstan to detect tuberculosis (TB) and rifampici...
INTRODUCTION:Rapid tests for rifampicin resistance may be useful for identifying isolates at high ri...
Journal Article; Research Support, Non-U.S. Gov't;BACKGROUND Nucleic acid amplification tests are i...
INTRODUCTION:Despite recent diagnostic advances, the majority of multidrug-resistant tuberculosis (M...
Objective: Tuberculosis is an important public health problem in developed and, especially, developi...
<div><p>Background</p><p>The aim of this study was to compare the performance of several recently de...
BackgroundThe aim of this study was to compare the performance of several recently developed assays ...
Pulmonary tuberculosis still remains a major communicable disease worldwide. In 2013, 9 million peop...
Performance evaluation of three commercial molecular assays for the detection of Mycobacterium tuber...
Background: The Xpert MTB/RIF assay has garnered significant interest as a sensitive and rapid diagn...
Background The Xpert1MTB/RIF (Xpert) is an automated molecular test for simultaneous detection of tu...
Background In India as elsewhere, multi-drug resistance (MDR) poses a serious challenge in the contr...
to multidrug-resistant tuberculosis diagnosis and treatment initiation: a qualitative comparison of ...
Background: An algorithm instituted following Xpert MTB/RIF (Xpert) introduction in South Africa adv...
commercial assays for the detection of Mycobacterium tuberculosis complex (MTBC), Xpert MTB/RIF (Cep...
Background Xpert MTB/RIF (Xpert) was piloted in Kazakhstan to detect tuberculosis (TB) and rifampici...
INTRODUCTION:Rapid tests for rifampicin resistance may be useful for identifying isolates at high ri...
Journal Article; Research Support, Non-U.S. Gov't;BACKGROUND Nucleic acid amplification tests are i...
INTRODUCTION:Despite recent diagnostic advances, the majority of multidrug-resistant tuberculosis (M...
Objective: Tuberculosis is an important public health problem in developed and, especially, developi...