RESEARCH ARTICLE The fruit extract of Berberi

lin ce cr ion s crataegina DC. and its hybrids are widely distributed condensed aqueous extract of B. oblonga root is reported Charehsaz et al. DARU Journal of Pharmaceutical Sciences (2015) 23:24 DOI 10.1186/s40199-015-0108-7report, the fruit paste of B. crataegina has been used to34755 Atasehir, Istanbul, Turkey Full list of author information is available at the end of the articleand its black fruits are often consumed as food, and used as diuretic and expectorant. Moreover, the roots and root barks of this plant have been used in Turkish folk medicine against various ailments including jaundice, hemorrhoids, dysuria and as febrifuges in feverish condi-tions as well as tonic and appetizer [4,5]. On the other hand, the red fruits of another species, B. vulgaris L., have been used as a garniture in Persian food culture to be prescribed for the effective treatment of lumbago [8], while in Nepal, the condensed aqueous extract of B. asiatica Roxb. root barks is reported to be used orally against fever and in Pakistan powdered roots of B. lycium Royle are used orally with milk to treat rheumatic and muscular pains [5]. As summarized above, the underground parts of Berberis species have been used particularly against inflammatory disorders in worldwide traditional medicines, while the fruits of Berberis species have frequently been used as food, rather than for healing purposes. According to a recent * Correspondence