The impact of autonomic dysfunction on survival in patients with dementia with lewy bodies and Parkinson’s disease with dementia

Introduction: Autonomic dysfunction is a well-known feature in neurodegenerative dementias, especially common in a-synucleinopathies like dementia with Lewy bodies and Parkinson’s disease with dementia. The most common symptoms are orthostatic hypotension, incontinence and constipation, but its relevance in clinical practice is poorly understood. There are no earlier studies addressing the influence of autonomic dysfunction on clinical course and survival. The aim of this study was to investigate the frequency of the three most common features of autonomic dysfunction and analyze how it affect