Background: Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins found only in nematodes. They are synthesized as large, tandemly repetitive polyproteins that are post-translationally cleaved into multiple copies of small lipid binding proteins with virtually identical fatty acid and retinol (Vitamin A)-binding characteristics. They are probably central to transport and distribution of small hydrophobic compounds between the tissues of nematodes, and may play key roles in nutrient scavenging, immunomodulation, and IgE antibody-based responses in infection. In some species the repeating units are diverse in amino acid sequence, but, in ascarid and filarial nematodes, many of the units are identical or near-ide...
Parasitic nematodes cause a wide range of diseases in humans, including river blindness caused by On...
Intracellular lipid-binding proteins (iLBPs) of the fatty acid-binding protein (FABP) family of anim...
The structure of the Ascaris allergen, ABA-1 was characterized at several levels. Purified allergen ...
Parasitic nematode worms cause serious health problems in humans and other animals. They can induce ...
Background: Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins fou...
Parasitic nematode worms cause serious health problems in humans and other animals. They can induce ...
We are engaged in structural and functional studies of several types of lipid binding protein that a...
The polyprotein allergens/antigens of nematodes (NPAs) are the only lipid binding proteins known to ...
The polyprotein allergens/antigens of nematodes (NPAs) are the only lipid binding proteins known to ...
, the large intestinal roundworm of humans. Immune responses to NPAs have been associated with natur...
Polyproteins comprise long polypeptides that are post-translationally cleaved into proteins of diffe...
Nematodes produce two classes of small, helix-rich fatty acid- and retinol-binding proteins whose st...
Parasitic nematodes have recently been found to produce proteins which represent two new classes of ...
The ABA-1 protein of Ascaris lumbricoides (of humans) and Ascaris suum (of pigs) is abundant in the ...
The ABA-1 protein of Ascaris lumbricoides (of humans) and Ascaris suum (of pigs) is abundant in the ...
Parasitic nematodes cause a wide range of diseases in humans, including river blindness caused by On...
Intracellular lipid-binding proteins (iLBPs) of the fatty acid-binding protein (FABP) family of anim...
The structure of the Ascaris allergen, ABA-1 was characterized at several levels. Purified allergen ...
Parasitic nematode worms cause serious health problems in humans and other animals. They can induce ...
Background: Nematode polyprotein allergens (NPAs) are an unusual class of lipid-binding proteins fou...
Parasitic nematode worms cause serious health problems in humans and other animals. They can induce ...
We are engaged in structural and functional studies of several types of lipid binding protein that a...
The polyprotein allergens/antigens of nematodes (NPAs) are the only lipid binding proteins known to ...
The polyprotein allergens/antigens of nematodes (NPAs) are the only lipid binding proteins known to ...
, the large intestinal roundworm of humans. Immune responses to NPAs have been associated with natur...
Polyproteins comprise long polypeptides that are post-translationally cleaved into proteins of diffe...
Nematodes produce two classes of small, helix-rich fatty acid- and retinol-binding proteins whose st...
Parasitic nematodes have recently been found to produce proteins which represent two new classes of ...
The ABA-1 protein of Ascaris lumbricoides (of humans) and Ascaris suum (of pigs) is abundant in the ...
The ABA-1 protein of Ascaris lumbricoides (of humans) and Ascaris suum (of pigs) is abundant in the ...
Parasitic nematodes cause a wide range of diseases in humans, including river blindness caused by On...
Intracellular lipid-binding proteins (iLBPs) of the fatty acid-binding protein (FABP) family of anim...
The structure of the Ascaris allergen, ABA-1 was characterized at several levels. Purified allergen ...