Clinical Study Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2 % Fluconazole on Fungal Keratitis

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose. To evaluate effects of lamellar keratectomy and intrastromal injection of 0.2 % fluconazole (LKIIF) on fungal keratitis. Methods. Data for 54 eyes of consecutive patients with fungal keratitis treated with LKIIF were retrospectively analyzed.The lesions in these eyes did not heal or were aggravated after antifungal chemotherapy for 7 days.Themaximum lesion diameters were ≤5mm andmaximum depth was not more than half of full corneal thickness. Cases were followed up for at least 90 days. Results. Forty-six eyes were cured (85.2%). The wound healing times were 3–16 days and were less than 7 days in 28 cases (51.9%). In cured eyes, uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) were both 20/250–20/20. The UCVA improved in 38 eyes andwas unchanged in seven eyes. BCVA improved in 44 eyes andwas unchanged in two eyes.When followed up formore tha