Background: Genome-wide association studies (GWAS) have identified several breast cancer susceptibility loci, and one genetic variant, rs11249433, at 1p11.2 was reported to be associated with breast cancer in European populations. To explore the genetic variants in this region associated with breast cancer in Chinese women, we conducted a two-stage fine-mapping study with a total of 1792 breast cancer cases and 1867 controls. Methodology/Principal Findings: Seven single nucleotide polymorphisms (SNPs) including rs11249433 in a 277 kb region at 1p11.2 were selected and genotyping was performed by using TaqManH OpenArrayTM Genotyping System for stage 1 samples (878 cases and 900 controls). In stage 2 (914 cases and 967 controls), three SNPs (...
Known risk variants explain only a small proportion of breast cancer heritability, particularly in A...
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian ancestry, ...
We evaluated the generalizability of a single nucleotide polymorphism (SNP), rs2046210 (A/G allele),...
BACKGROUND: Genome-wide association studies (GWAS) have identified several breast cancer susceptibil...
Although approximately 20 common genetic susceptibility loci have been identified for breast cancer ...
A recent genome-wide association study (GWAS) has identified three new breast cancer susceptibility ...
Some of the new breast cancer susceptibility loci discovered in recent Genome-wide association studi...
BACKGROUND: We previously conducted a systematic field synopsis of 1059 breast cancer candidate gene...
Background: Approximately 100 common breast cancer susceptibility alleles have been identified in ge...
Over the past 20 years, high-penetrance pathogenic mutations in genes BRCA1, BRCA2, TP53, PTEN, STK1...
The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identif...
Over the past 20 years, high-penetrance pathogenic mutations in genes BRCA1, BRCA2, TP53, PTEN, STK1...
The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identif...
Known risk variants explain only a small proportion of breast cancer heritability, particularly in A...
The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identif...
Known risk variants explain only a small proportion of breast cancer heritability, particularly in A...
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian ancestry, ...
We evaluated the generalizability of a single nucleotide polymorphism (SNP), rs2046210 (A/G allele),...
BACKGROUND: Genome-wide association studies (GWAS) have identified several breast cancer susceptibil...
Although approximately 20 common genetic susceptibility loci have been identified for breast cancer ...
A recent genome-wide association study (GWAS) has identified three new breast cancer susceptibility ...
Some of the new breast cancer susceptibility loci discovered in recent Genome-wide association studi...
BACKGROUND: We previously conducted a systematic field synopsis of 1059 breast cancer candidate gene...
Background: Approximately 100 common breast cancer susceptibility alleles have been identified in ge...
Over the past 20 years, high-penetrance pathogenic mutations in genes BRCA1, BRCA2, TP53, PTEN, STK1...
The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identif...
Over the past 20 years, high-penetrance pathogenic mutations in genes BRCA1, BRCA2, TP53, PTEN, STK1...
The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identif...
Known risk variants explain only a small proportion of breast cancer heritability, particularly in A...
The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identif...
Known risk variants explain only a small proportion of breast cancer heritability, particularly in A...
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian ancestry, ...
We evaluated the generalizability of a single nucleotide polymorphism (SNP), rs2046210 (A/G allele),...