RESEARCH ARTICLE Shift Work and the Relationship with Metabolic Syndrome in Chinese Aged Workers

Background Shift work is indicated to be associated with adverse metabolic disorders. However, poten-tial effects of shift work on metabolic syndrome (MetS) and its components have not been well established. Methods In total, 26,382 workers from Dongfeng-Tongji Cohort were included in this study. Informa-tion on shift work history was gathered through questionnaires and metabolic traits were measured. Logistic regression models were used to calculate the odds ratio (OR) and 95% confidence interval (CI) for long-term shift work related with MetS and each component, re-spectively. Further stratification analysis was performed to detect the differences on MetS between female and male shift workers. Results Long-term shift work was associated with MetS without adjusting for any confounders. Com-pared with the group of non-shift work, the multivariate-adjusted ORs (95%CI) of MetS as