Add to ORKGCopyright © 2015 Junghyun Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Aldose reductase (AR) is the first and rate-limiting enzyme of the polyol pathway. AR-dependent synthesis of excess polyols leads to lens opacification in diabetic cataract. The purpose of this study is to investigate the protective effect of Litsea japonica extract (LJE) on diabetes-induced lens opacification and its protective mechanism in db/db mice. Seven-week-old male db/db mice were treated with LJE (100 and 250mg/kg body weight) once a day orally for 12 weeks. LJE dose dependently inhib...
Background: A variety of causative factors are involved in the initiation of diabetic retinopathy (D...
Blinding cataract is a significant effect of canine diabetes with 75% of animals affected two years ...
Copyright © 2013 Claudio Bucolo et al.This is an open access article distributed under the Creative ...
Increasing evidence indicates that advanced glycation end products (AGEs) contribute to the pathogen...
Copyright © 2013 Junghyun Kim et al. This is an open access article distributed under the Creative C...
Introduction: Diabetic retinopathy is a late stage complication in diabetic patients and one which d...
Aim: The aim of the research work was to carried out the antidiabitic inhibitory potential of the fr...
Diabetes mellitus is a chronic disorder characterized by persistent elevated blood glucose level in ...
The present study was intended to evaluate, highlight and explore the role of four medicinal plant (...
Aldose reductase (AR) has been implicated in the etiology of diabetic cataract, as well as in other ...
Copyright © 2012 Chandrasekhar Akileshwari et al. This is an open access article distributed under t...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Background. Increased activity of aldose reductase (AR) is one of the mechanisms involved in the dev...
One of the earliest critical secondary complications of diabetes is the opacification of the eye len...
Background: Several metabolic pathways are involved in the complications of diabetes like polyol pat...
Background: A variety of causative factors are involved in the initiation of diabetic retinopathy (D...
Blinding cataract is a significant effect of canine diabetes with 75% of animals affected two years ...
Copyright © 2013 Claudio Bucolo et al.This is an open access article distributed under the Creative ...
Increasing evidence indicates that advanced glycation end products (AGEs) contribute to the pathogen...
Copyright © 2013 Junghyun Kim et al. This is an open access article distributed under the Creative C...
Introduction: Diabetic retinopathy is a late stage complication in diabetic patients and one which d...
Aim: The aim of the research work was to carried out the antidiabitic inhibitory potential of the fr...
Diabetes mellitus is a chronic disorder characterized by persistent elevated blood glucose level in ...
The present study was intended to evaluate, highlight and explore the role of four medicinal plant (...
Aldose reductase (AR) has been implicated in the etiology of diabetic cataract, as well as in other ...
Copyright © 2012 Chandrasekhar Akileshwari et al. This is an open access article distributed under t...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Background. Increased activity of aldose reductase (AR) is one of the mechanisms involved in the dev...
One of the earliest critical secondary complications of diabetes is the opacification of the eye len...
Background: Several metabolic pathways are involved in the complications of diabetes like polyol pat...
Background: A variety of causative factors are involved in the initiation of diabetic retinopathy (D...
Blinding cataract is a significant effect of canine diabetes with 75% of animals affected two years ...
Copyright © 2013 Claudio Bucolo et al.This is an open access article distributed under the Creative ...