LETTER TO THE EDITOR

Kawasaki disease patients homozygous for the rs12252-C variant of interferon-induced transmembrane protein-3 are significantly more likely to develop coronary artery lesions doi: 10.1002/mgg3.79 Kawasaki disease (KD) is the most common systemic vas-culitis syndrome, primarily affecting small- to medium-sized arteries, more particularly the coronary arteries (Kato et al. 1996). KD was first described in 1967 and is now identified as the leading cause of acquired heart dis-ease among children in developed countries (Wang et al. 2005). The annual incidence of KD in children of Japa-nese descent is about 218 per 100,000 children less than 5 years of age (Nakamura et al. 2012) as compared to about 20 per 100,000 in the United States (Holman et al. 2010a). Timely treatment with high-dose intravenous