Add to ORKGABSTRACT: The photoredox-mediated coupling of benzylic ethers with Schiff bases has been accomplished. Direct benzylic C−H activation by a combination of a thiol catalyst with an iridium photocatalyst and subsequent radical−radical coupling with secondary aldimines affords a variety of β-amino ether products in good to excellent yields. Mechanistic studies suggest that a reductive quenching pathway of the photocatalyst is operable. The direct and controlled C−H functionalization of sp3-hybridized carbons has become a challenging goal in modern synthetic organic chemistry.1 In this context, our laboratory has recently introduced a protocol that allows the activation and subsequent arylation of benzylic C−H bonds via the cooperative action of...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Over the past decade, a resurgence of interest in photo-induced electron transfer has resulted in a ...
The photoredox-mediated coupling of benzylic ethers with Schiff bases has been accomplished. Direct ...
Direct C–H functionalization and arylation of benzyl ethers has been accomplished via photoredox org...
We report a radical-based organocatalytic method for the direct benzylation of allylic C–H bonds. Th...
We report a radical-based organocatalytic method for the direct benzylation of allylic C–H bonds. Th...
An unprecedented method that makes use of the cooperative interplay between molecular iodine and pho...
In the modern era of chemistry, photoredox catalysis has proven its usefulness in many synthetic app...
Transition metal-catalysed processes have been widely used for the functionalization of inert C−H bo...
Access to C<i>sp</i><sup>2</sup>–C<i>sp</i><sup>3</sup>-coupled products is a challenging goal at th...
ABSTRACT: Direct β-alkylation of saturated aldehydes has been accomplished by synergistically combin...
Alkyl radicals are powerful intermediates for the generation of carbon-carbon bonds, which play a...
Aryl–aryl cross-coupling constitutes one of the most widely used procedures for the synthesis of hig...
Methods for the direct C−H functionalization of aromatic compounds are in demand for a variety of ap...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Over the past decade, a resurgence of interest in photo-induced electron transfer has resulted in a ...
The photoredox-mediated coupling of benzylic ethers with Schiff bases has been accomplished. Direct ...
Direct C–H functionalization and arylation of benzyl ethers has been accomplished via photoredox org...
We report a radical-based organocatalytic method for the direct benzylation of allylic C–H bonds. Th...
We report a radical-based organocatalytic method for the direct benzylation of allylic C–H bonds. Th...
An unprecedented method that makes use of the cooperative interplay between molecular iodine and pho...
In the modern era of chemistry, photoredox catalysis has proven its usefulness in many synthetic app...
Transition metal-catalysed processes have been widely used for the functionalization of inert C−H bo...
Access to C<i>sp</i><sup>2</sup>–C<i>sp</i><sup>3</sup>-coupled products is a challenging goal at th...
ABSTRACT: Direct β-alkylation of saturated aldehydes has been accomplished by synergistically combin...
Alkyl radicals are powerful intermediates for the generation of carbon-carbon bonds, which play a...
Aryl–aryl cross-coupling constitutes one of the most widely used procedures for the synthesis of hig...
Methods for the direct C−H functionalization of aromatic compounds are in demand for a variety of ap...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Over the last decade, visible-light photoredox catalysis is rising as an important route for new che...
Over the past decade, a resurgence of interest in photo-induced electron transfer has resulted in a ...