ABSTRACT: Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgical methods for repairing or replacing such damage have limitations. Tissue engineering offers a potential alternative. Here we show that functionalized α-helical-peptide hydrogels can be used to induce attachment, migration, proliferation and differentiation of murine embryonic neural stem cells (NSCs). Specifically, compared with undecorated gels, those functionalized with Arg-Gly-Asp-Ser (RGDS) peptides increase the proliferative activity of NSCs; promote their directional migration; induce differentiation, with increased expression of microtubule-associated protein-2, and a low expression of glial fibrillary acidic protein; and l...
The increasing incidence of neurodegenerative diseases such as Alzheimer’s or Parkinson's disease re...
The increasing incidence of neurodegenerative diseases such as Alzheimer’s or Parkinson's disease re...
Brain injury is almost irreparable due to the poor regenerative capability of neural tissue. Nowaday...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
This is the final version of the article. Available from the American Chemical Society via the DOI i...
The number of individuals affected by neurological disorders rises rapidly world-wide, however, ther...
The increasing incidence of neurodegenerative diseases such as Alzheimer’s or Parkinson's disease re...
The increasing incidence of neurodegenerative diseases such as Alzheimer’s or Parkinson's disease re...
Brain injury is almost irreparable due to the poor regenerative capability of neural tissue. Nowaday...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
Trauma to the central and peripheral nervous systems often lead to serious morbidity. Current surgic...
This is the final version of the article. Available from the American Chemical Society via the DOI i...
The number of individuals affected by neurological disorders rises rapidly world-wide, however, ther...
The increasing incidence of neurodegenerative diseases such as Alzheimer’s or Parkinson's disease re...
The increasing incidence of neurodegenerative diseases such as Alzheimer’s or Parkinson's disease re...
Brain injury is almost irreparable due to the poor regenerative capability of neural tissue. Nowaday...