Rab29 (also referred as Rab7L1) is a novel Rab protein, and is recently demonstrated to regulate phagocytosis and traffic from the Golgi to the lysosome. However, its roles in membrane trafficking have not been investigated extensively. Our results in this study revealed that Rab29 is associated with the trans-Golgi network (TGN), and is essential for maintaining the integrity of the TGN, because inhibition of the activity of Rab29 or depletion of Rab29 resulted in fragmentation of the TGN marked by TGN46. Expression of the dominant negative form Rab29T21N or shRNA-Rab29 also altered the distribution of mannose-6-phosphate receptor (M6PR), and interrupted the retrograde trafficking of M6PR through monitoring the endocytosis of CD8-tagged ca...
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport...
The retromer complex mediates retrograde transport of transmembrane cargo from endosomes to the tran...
Rab GTPases are master regulators of membrane traffic. By binding to distinct sets of effector prote...
Rab29 (also referred as Rab7L1) is a novel Rab protein, and is recently demonstrated to regulate pha...
<div><p>Rab29 (also referred as Rab7L1) is a novel Rab protein, and is recently demonstrated to regu...
Rab7b is a recently identified member of the Rab GTPase protein family and has high similarity to Ra...
Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identifie...
Background: Golgi-localized Rab34 has been implicated in repositioning of lysosomes and activation o...
Rab31, a protein that we cloned from an oligodendrocyte cDNA library, is required for transport of m...
Contains fulltext : 71292.pdf (publisher's version ) (Open Access)Small GTPases of...
members of the mammalian Rab protein family group into subfamilies postulated to share common funct...
These authors contributed equally to this work. The closely related Rab6 isoforms, Rab6A and Rab6A’,...
Background: The 60+ members of the mammalian Rab protein family group into subfamilies postulated to...
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport...
<p>A,B. HeLa cells were co-transfected CD8-cdM6PR or CD8-ciM6PR with myc-Rab29WT, Rab29T21N or vecto...
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport...
The retromer complex mediates retrograde transport of transmembrane cargo from endosomes to the tran...
Rab GTPases are master regulators of membrane traffic. By binding to distinct sets of effector prote...
Rab29 (also referred as Rab7L1) is a novel Rab protein, and is recently demonstrated to regulate pha...
<div><p>Rab29 (also referred as Rab7L1) is a novel Rab protein, and is recently demonstrated to regu...
Rab7b is a recently identified member of the Rab GTPase protein family and has high similarity to Ra...
Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identifie...
Background: Golgi-localized Rab34 has been implicated in repositioning of lysosomes and activation o...
Rab31, a protein that we cloned from an oligodendrocyte cDNA library, is required for transport of m...
Contains fulltext : 71292.pdf (publisher's version ) (Open Access)Small GTPases of...
members of the mammalian Rab protein family group into subfamilies postulated to share common funct...
These authors contributed equally to this work. The closely related Rab6 isoforms, Rab6A and Rab6A’,...
Background: The 60+ members of the mammalian Rab protein family group into subfamilies postulated to...
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport...
<p>A,B. HeLa cells were co-transfected CD8-cdM6PR or CD8-ciM6PR with myc-Rab29WT, Rab29T21N or vecto...
Rab proteins represent a large family of ras-like GTPases that regulate distinct vesicular transport...
The retromer complex mediates retrograde transport of transmembrane cargo from endosomes to the tran...
Rab GTPases are master regulators of membrane traffic. By binding to distinct sets of effector prote...