Clostridium difficile is considered to be one of the most important causes of health care-associated infections worldwide. In order to understand more fully the adaptive response of the organism to stressful conditions, we examined transcriptional changes resulting from a clinically relevant heat stress (41uC versus 37uC) in C. difficile strain 630 and identified 341 differentially expressed genes encompassing multiple cellular functional categories. While the transcriptome was relatively resilient to the applied heat stress, we noted upregulation of classical heat shock genes including the groEL and dnaK operons in addition to other stress-responsive genes. Interestingly, the flagellin gene (fliC) was downregulated, yet genes encoding the ...
C. difficile is the most common cause of nosocomial diarrhea in North America and Europe. Genomes of...
The development of molecular tools allowed light to be shed on several widespread genetic mechanisms...
Bacteria encode heat shock proteins that aid in survival during stressful growth conditions. In addi...
Clostridium difficile is considered to be one of the most important causes of health care-associated...
Clostridium difficile has raised significant public concern over the past few decades owing to its e...
Clostridium difficile is considered to be the most frequent cause of infectious bacterial diarrhoea ...
Clostridium difficile is a serious nosocomial pathogen whose prevalence worldwide is increasing. Pos...
Clostridium difficile is a spore-forming anaerobic bacterium that is an emerging nosocomial threat; ...
<div><p><i>Clostridium difficile</i> is considered to be the most frequent cause of infectious bacte...
Clostridium difficile is a serious nosocomial pathogen whose prevalence worldwide is increasing. Pos...
Clostridium difficile infection is a growing problem in healthcare settings worldwide and results in...
International audienceOur laboratory has previously shown that adherence of Clostridium difficile to...
peer reviewedDeinococcus radiodurans is best known for its extraordinary resistance to diverse envir...
Desulfovibrio vulgaris Hildenborough belongs to a class of sulfate-reducing bacteria (SRB) and is fo...
Copyright © 2013 Wan-dong Liang et al. This is an open access article distributed under the Creative...
C. difficile is the most common cause of nosocomial diarrhea in North America and Europe. Genomes of...
The development of molecular tools allowed light to be shed on several widespread genetic mechanisms...
Bacteria encode heat shock proteins that aid in survival during stressful growth conditions. In addi...
Clostridium difficile is considered to be one of the most important causes of health care-associated...
Clostridium difficile has raised significant public concern over the past few decades owing to its e...
Clostridium difficile is considered to be the most frequent cause of infectious bacterial diarrhoea ...
Clostridium difficile is a serious nosocomial pathogen whose prevalence worldwide is increasing. Pos...
Clostridium difficile is a spore-forming anaerobic bacterium that is an emerging nosocomial threat; ...
<div><p><i>Clostridium difficile</i> is considered to be the most frequent cause of infectious bacte...
Clostridium difficile is a serious nosocomial pathogen whose prevalence worldwide is increasing. Pos...
Clostridium difficile infection is a growing problem in healthcare settings worldwide and results in...
International audienceOur laboratory has previously shown that adherence of Clostridium difficile to...
peer reviewedDeinococcus radiodurans is best known for its extraordinary resistance to diverse envir...
Desulfovibrio vulgaris Hildenborough belongs to a class of sulfate-reducing bacteria (SRB) and is fo...
Copyright © 2013 Wan-dong Liang et al. This is an open access article distributed under the Creative...
C. difficile is the most common cause of nosocomial diarrhea in North America and Europe. Genomes of...
The development of molecular tools allowed light to be shed on several widespread genetic mechanisms...
Bacteria encode heat shock proteins that aid in survival during stressful growth conditions. In addi...