Development and patterning of neural tissue in the vertebrate embryo involves a set of molecules and processes whose relationships are not fully understood. Classical embryology revealed a remarkable phenomenon known as vertical signalling, a gastrulation stage mechanism that copies anterior-posterior positional information from mesoderm to prospective neural tissue. Vertical signalling mediates unambiguous copying of complex information from one tissue layer to another. In this study, we report an investigation of this process in recombinates of mesoderm and ectoderm from gastrulae of Xenopus laevis. Our results show that copying of positional information involves non cell autonomous autoregulation of particular Hox genes whose expression ...
AbstractHox genes encode a family of transcription factors that specify positional identities along ...
Neural pattern in vertebrates has been thought to be induced in dorsal ectoderm by 'vertical &a...
The Xenopus homeobox gene Xhox3 shows a graded expression in the axial mesoderm, with the highest co...
<div><p>Development and patterning of neural tissue in the vertebrate embryo involves a set of molec...
During early vertebrate embryogenesis, cell fate specification is often coupled with cell acquisitio...
The research described in this thesis mainly focussed on making and refining a model that describes ...
Hox genes are a very important family of transcription factors during development of vertebrate and ...
AbstractIn this paper we examine the contributions of planar and vertical signaling to the patternin...
AbstractWe report a novel developmental mechanism. Anterior–posterior positional information for the...
During animal development, the early embryo undergoes gastrulation to bring the primary germ layers ...
The Hox genes form a subset of the homeobox containing genes. The homeobox encodes a DNA binding mot...
Cell migration, usually seen as a relatively well understood phenomenon, is involved in many aspects...
My PhD project studies how the temporally sequential Hox gene expression is regulat...
Background: One way in which positional information is established during embryonic development is t...
AbstractDorsal-ventral patterning in Xenopus and Drosophila embryos involves BMP family signalling m...
AbstractHox genes encode a family of transcription factors that specify positional identities along ...
Neural pattern in vertebrates has been thought to be induced in dorsal ectoderm by 'vertical &a...
The Xenopus homeobox gene Xhox3 shows a graded expression in the axial mesoderm, with the highest co...
<div><p>Development and patterning of neural tissue in the vertebrate embryo involves a set of molec...
During early vertebrate embryogenesis, cell fate specification is often coupled with cell acquisitio...
The research described in this thesis mainly focussed on making and refining a model that describes ...
Hox genes are a very important family of transcription factors during development of vertebrate and ...
AbstractIn this paper we examine the contributions of planar and vertical signaling to the patternin...
AbstractWe report a novel developmental mechanism. Anterior–posterior positional information for the...
During animal development, the early embryo undergoes gastrulation to bring the primary germ layers ...
The Hox genes form a subset of the homeobox containing genes. The homeobox encodes a DNA binding mot...
Cell migration, usually seen as a relatively well understood phenomenon, is involved in many aspects...
My PhD project studies how the temporally sequential Hox gene expression is regulat...
Background: One way in which positional information is established during embryonic development is t...
AbstractDorsal-ventral patterning in Xenopus and Drosophila embryos involves BMP family signalling m...
AbstractHox genes encode a family of transcription factors that specify positional identities along ...
Neural pattern in vertebrates has been thought to be induced in dorsal ectoderm by 'vertical &a...
The Xenopus homeobox gene Xhox3 shows a graded expression in the axial mesoderm, with the highest co...