In asthmatic individuals, airway narrowing represents the early phase of the asthmatic response to allergen inhalation challenge, occurring within thirty minutes [1]. In 50-60 % of allergic asthmatic adults, the early response is followed by the late phase asthmatic response, usually starting between 3-4 hours after aller-gen inhalation challenge [2], and characterized mainly by cellular inflammation of the airway [3]. The pathways leading to the late response are not completely under-stood. Understanding these pathways is important for evaluating allergic diseases such as asthma. In contrast to the more transient isolated early response, develop-ment of the late response is associated with the hall-mark inflammatory features of chronic all...
Prevalence of allergy and allergic asthma are increasing worldwide. More than half of the US populat...
BACKGROUND: Allergen inhalation challenge in asthma may induce both early (EAR) and late (LAR) asthm...
Allergen bronchoprovocation of the airways in sensitised asthmatic subjects provokes changes similar...
Allergen inhalation challenge (AIC) triggers biphasic responses in allergic asthmatic individuals. ...
Individuals with allergic asthma respond differently, but reproducibly, to allergen inhalation chall...
Some asthmatic individuals undergoing allergen inhalation challenge develop an isolated early respon...
Other UBCNon UBCMedicine, Faculty ofMedicine, Department ofRespiratory Medicine, Division ofReviewed...
Increasing insights into the mechanism underlying the allergen-induced late asthmatic response (LAR)...
Allergic rhinitis (AR) is a heterogeneous disorder that is associated with inflammation of the upper...
Background: A subset of individuals with allergic asthma develops a late phase response (LPR) to inh...
Small maladaptations in cellular response to environmental stressors may underlie diseases like asth...
Asthma is a chronic inflammatory airway disorder characterized by reversible airway obstruction and ...
Allergen inhalation challenge causes significant changes in the blood transcriptomes of mild atopic ...
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN024151 / BLDSC - British Library D...
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in...
Prevalence of allergy and allergic asthma are increasing worldwide. More than half of the US populat...
BACKGROUND: Allergen inhalation challenge in asthma may induce both early (EAR) and late (LAR) asthm...
Allergen bronchoprovocation of the airways in sensitised asthmatic subjects provokes changes similar...
Allergen inhalation challenge (AIC) triggers biphasic responses in allergic asthmatic individuals. ...
Individuals with allergic asthma respond differently, but reproducibly, to allergen inhalation chall...
Some asthmatic individuals undergoing allergen inhalation challenge develop an isolated early respon...
Other UBCNon UBCMedicine, Faculty ofMedicine, Department ofRespiratory Medicine, Division ofReviewed...
Increasing insights into the mechanism underlying the allergen-induced late asthmatic response (LAR)...
Allergic rhinitis (AR) is a heterogeneous disorder that is associated with inflammation of the upper...
Background: A subset of individuals with allergic asthma develops a late phase response (LPR) to inh...
Small maladaptations in cellular response to environmental stressors may underlie diseases like asth...
Asthma is a chronic inflammatory airway disorder characterized by reversible airway obstruction and ...
Allergen inhalation challenge causes significant changes in the blood transcriptomes of mild atopic ...
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN024151 / BLDSC - British Library D...
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in...
Prevalence of allergy and allergic asthma are increasing worldwide. More than half of the US populat...
BACKGROUND: Allergen inhalation challenge in asthma may induce both early (EAR) and late (LAR) asthm...
Allergen bronchoprovocation of the airways in sensitised asthmatic subjects provokes changes similar...