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Full list of author information is available at the end of the articlecervical cancer is either radical surgery or radiotherapy. However, effective treatment options for patients with lo-cally advanced cervical cancer are limited [2]. As 99 % of cervical lesions contain viral sequences, the causative factors attributed to the immortalization and malignant transformation of cervical cells. They present growth-stimulating and transforming properties [4]. HPV onco-gene subtype, E6 and E7, interfere with cellular functions of tumor suppressor proteins and extend the proliferative capacity of infected cells by blocking apoptosis [5]. Apoptosis, also known as programmed cell death, plays a crucial role in development, morphogenesis, normal cell turnover and immune system function [6]. Acquired resistance to apoptosis is a well-known hall-mark of cancer and contributes to tumorigenesis an