of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5 ′ splice site strengt
AbstractAlternative splicing is a key mechanism for generating proteome diversity, however the mecha...
Altered splicing of transcripts encoding proteins required for mitotic progression after PRPF8 deple...
The removal of introns from precursor messenger RNAs occurs in a large complex, the spliceosome, tha...
BACKGROUND: Sequential assembly of the human spliceosome on RNA transcripts regulates splicing acros...
BACKGROUND: Sequential assembly of the human spliceosome on RNA transcripts regulates splicing acros...
Transcription initiation is similar in control siRNA-treated and PRPF8-depleted cells. a Delay betwe...
Enhancement of 3′ splice-site strength renders the CDC20 mini-gene resistant to PRPF8 depletion. a A...
Validation of PRPF8 depletion. a Validation of PRPF8 depletion by qRTPCR. Results are plotted relati...
Genome-wide decreases in spliceosome assembly at intron–exon junctions following PRPF8 depletion are...
Inefficiently spliced introns and exons that are differentially used do not have weaker 3′ splice si...
Prp8 is an essential protein that regulates spliceosome assembly and conformation during pre-mRNA sp...
Alternative splicing is a key mechanism for generating proteome diversity, however the mechanisms re...
Validation of mitotic arrest following PRPF8 depletion with two independent siRNAs. a U2OS osteosarc...
Depletion of Complex B components that interact directly with PRPF8 recapitulate defects in mitotic ...
Alternative splicing plays an essential role in various physiological processes such as cellular dif...
AbstractAlternative splicing is a key mechanism for generating proteome diversity, however the mecha...
Altered splicing of transcripts encoding proteins required for mitotic progression after PRPF8 deple...
The removal of introns from precursor messenger RNAs occurs in a large complex, the spliceosome, tha...
BACKGROUND: Sequential assembly of the human spliceosome on RNA transcripts regulates splicing acros...
BACKGROUND: Sequential assembly of the human spliceosome on RNA transcripts regulates splicing acros...
Transcription initiation is similar in control siRNA-treated and PRPF8-depleted cells. a Delay betwe...
Enhancement of 3′ splice-site strength renders the CDC20 mini-gene resistant to PRPF8 depletion. a A...
Validation of PRPF8 depletion. a Validation of PRPF8 depletion by qRTPCR. Results are plotted relati...
Genome-wide decreases in spliceosome assembly at intron–exon junctions following PRPF8 depletion are...
Inefficiently spliced introns and exons that are differentially used do not have weaker 3′ splice si...
Prp8 is an essential protein that regulates spliceosome assembly and conformation during pre-mRNA sp...
Alternative splicing is a key mechanism for generating proteome diversity, however the mechanisms re...
Validation of mitotic arrest following PRPF8 depletion with two independent siRNAs. a U2OS osteosarc...
Depletion of Complex B components that interact directly with PRPF8 recapitulate defects in mitotic ...
Alternative splicing plays an essential role in various physiological processes such as cellular dif...
AbstractAlternative splicing is a key mechanism for generating proteome diversity, however the mecha...
Altered splicing of transcripts encoding proteins required for mitotic progression after PRPF8 deple...
The removal of introns from precursor messenger RNAs occurs in a large complex, the spliceosome, tha...