RESEARCH ARTICLE Changes in the gene expr e

Full list of author information is available at the end of the articleBackground Animal reproduction depends on the precise timing and coordination of behavioral and physiological processes. For successful reproduction to occur, animals need to reach the appropriate developmental stage, locate and attract mates and respond appropriately to reproduc-tively relevant signals. The accuracy of each aspect of reproduction is essential to ensure that genetic material is passed on to the next generation. A major function of the brain is to establish the appro-priate developmental and endocrine status for reproduc-tion, and then to co-ordinate this with aspects of behavior and sexual maturation. In vertebrates, this coordination is established through the hypothalamus and pituitary gland [1]. The pituitary gland secretes follicle-stimulating hor