Add to ORKGCopyright © 2013 Wen-Juan Wang et al.This is an open access article distributed under theCreativeCommonsAttribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background/Objective. We aimed to examine the expression of lymphoid enhancer factor 1 (LEF1) and Notch2 in colorectal cancer (CRC) and their association with clinicopathologic variables and CRC patients ’ prognosis. Methods. Immunohistochemistry, quantitative real-time polymerase chain reaction (qRT-PCR), andWestern blot analysis were performed to assess the expression of LEF1 andNotch2 in 184 patients with CRC.Results.We observed a strong negative correlation between LEF1 expression andNotch2 e...
We have shown that LEF-1 protein is expressed in both HCT116 and SW480 colorectal cancer cell lines,...
BACKGROUND: Notch and Wnt pathways are key regulators of intestinal homeostasis and alterations in t...
Colorectal cancer (CRC) is the third most prevalent cancer all around the world. Chemotherapy plays ...
Expression of lymphoid enhancer factor 1 (LEF1) is frequently altered in different human cancers. Th...
Expression of lymphoid enhancer factor 1 (LEF1) is frequently altered in different human cancers. Th...
Background and Objectives: Although there was growing evidence supporting the hypothesis that Notch1...
Background/Purpose: Lymphoid-enhancing factor 1 (LEF1) is a transcription factor mediating Wnt/beta-...
Background: The purpose of this study was to evaluate the expression of Notch-induced transcription ...
<p>(A) Immunohistochemistry staining of LEF1 on paratumorous colon tissues (a) and colon cancer tiss...
We sought to identify genes of clinical significance to predict survival and the risk for colorectal...
Background: Most colorectal carcinomas are driven by an activation of the canonical Wnt signalling p...
Purpose: We sought to identify genes of clinical significance to predict survival and the risk for c...
Aberrantly activated Wnt signaling causes cellular transformation that can lead to human colorectal ...
PURPOSE:We sought to identify genes of clinical significance to predict survival and the risk for co...
The Notch signalling pathway is an evolutionary conserved pathway, named after the Notch receptors, ...
We have shown that LEF-1 protein is expressed in both HCT116 and SW480 colorectal cancer cell lines,...
BACKGROUND: Notch and Wnt pathways are key regulators of intestinal homeostasis and alterations in t...
Colorectal cancer (CRC) is the third most prevalent cancer all around the world. Chemotherapy plays ...
Expression of lymphoid enhancer factor 1 (LEF1) is frequently altered in different human cancers. Th...
Expression of lymphoid enhancer factor 1 (LEF1) is frequently altered in different human cancers. Th...
Background and Objectives: Although there was growing evidence supporting the hypothesis that Notch1...
Background/Purpose: Lymphoid-enhancing factor 1 (LEF1) is a transcription factor mediating Wnt/beta-...
Background: The purpose of this study was to evaluate the expression of Notch-induced transcription ...
<p>(A) Immunohistochemistry staining of LEF1 on paratumorous colon tissues (a) and colon cancer tiss...
We sought to identify genes of clinical significance to predict survival and the risk for colorectal...
Background: Most colorectal carcinomas are driven by an activation of the canonical Wnt signalling p...
Purpose: We sought to identify genes of clinical significance to predict survival and the risk for c...
Aberrantly activated Wnt signaling causes cellular transformation that can lead to human colorectal ...
PURPOSE:We sought to identify genes of clinical significance to predict survival and the risk for co...
The Notch signalling pathway is an evolutionary conserved pathway, named after the Notch receptors, ...
We have shown that LEF-1 protein is expressed in both HCT116 and SW480 colorectal cancer cell lines,...
BACKGROUND: Notch and Wnt pathways are key regulators of intestinal homeostasis and alterations in t...
Colorectal cancer (CRC) is the third most prevalent cancer all around the world. Chemotherapy plays ...