Xia-yu-xue decoction (XYXD) reduces carbon tetrachloride (CCl4)-induced liver fibrosis through inhibition hepatic stellate cell activation by targeting NF-κB and TGF-β1 signaling pathways Cheng Liu1†, Xia Yuan2†, Le Tao3, Zhuoan Cheng1, Xiuqin Dai1, Xia Sheng4 and Dongying Xue3* Background: Hepatic stellate cell (HSC) activation is activated mainly by endotoxin and transforming growth factor (TGF-β1) in chronic liver injury, consequently, can be important therapeutic targets. Xia-yu-xue decoction (XYXD), a classical recipe used in China to treat liver fibrosis, and has been revealed to inhibit hepatic fibrosis in animal models, the mechanism of action of XYXD remains elusive. In the present study, we evaluated whether XYXD reduced endotoxin...
Background: Hepatic fibrosis is caused by chronic liver injury and may progress toward liver cirrhos...
Abstract Background Huangqi decoction was first described in Prescriptions of the Bureau of Taiping ...
Introduction: Artemisia Capillaris Herba, a famous traditional Chinese medicine, is effective for th...
Background/Aims: Intestine-derived endotoxin is thought to play a role in the development of liver f...
Context Xiaoyaosan decoction (XYS), a classical Traditional Chinese Medicine (TCM) formula is used t...
Background/aims: Hepatic fibrosis is a consequence of severe liver damage that occurs in many patien...
ObjectiveTo investigate the therapeutic effect of Taohong Siwu decoction on a mouse model of carbon ...
Advanced liver fibrosis can lead to cirrhosis, resulting in an accelerated risk of hepatocellular ca...
Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver in...
Ethnopharmacological relevance: Pien-Tze-Huang (PZH)—a traditional Chinese medicine (TCM) compound—h...
BackgroundActivation of hepatic stellate cells (HSCs) is essential for the pathogenesis of liver fib...
Ethnopharmacological relevance: Pien-Tze-Huang (PZH)—a traditional Chinese medicine (TCM) compound—h...
Ethnopharmacological relevance: Hepatic fibrosis (HF) occurs in response to chronic liver injury and...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide...
Background. Fuzheng Huayu recipe (FZHY) is an original Chinese patent medicine which was developed a...
Background: Hepatic fibrosis is caused by chronic liver injury and may progress toward liver cirrhos...
Abstract Background Huangqi decoction was first described in Prescriptions of the Bureau of Taiping ...
Introduction: Artemisia Capillaris Herba, a famous traditional Chinese medicine, is effective for th...
Background/Aims: Intestine-derived endotoxin is thought to play a role in the development of liver f...
Context Xiaoyaosan decoction (XYS), a classical Traditional Chinese Medicine (TCM) formula is used t...
Background/aims: Hepatic fibrosis is a consequence of severe liver damage that occurs in many patien...
ObjectiveTo investigate the therapeutic effect of Taohong Siwu decoction on a mouse model of carbon ...
Advanced liver fibrosis can lead to cirrhosis, resulting in an accelerated risk of hepatocellular ca...
Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver in...
Ethnopharmacological relevance: Pien-Tze-Huang (PZH)—a traditional Chinese medicine (TCM) compound—h...
BackgroundActivation of hepatic stellate cells (HSCs) is essential for the pathogenesis of liver fib...
Ethnopharmacological relevance: Pien-Tze-Huang (PZH)—a traditional Chinese medicine (TCM) compound—h...
Ethnopharmacological relevance: Hepatic fibrosis (HF) occurs in response to chronic liver injury and...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide...
Background. Fuzheng Huayu recipe (FZHY) is an original Chinese patent medicine which was developed a...
Background: Hepatic fibrosis is caused by chronic liver injury and may progress toward liver cirrhos...
Abstract Background Huangqi decoction was first described in Prescriptions of the Bureau of Taiping ...
Introduction: Artemisia Capillaris Herba, a famous traditional Chinese medicine, is effective for th...