Background: Cyclin D1 (CCND1) plays a vital role in cancer cell cycle progression. Numerous epidemiological studies have evaluated the association between the CCND1 G870A polymorphism and the risk of colorectal cancer. However, these studies have yielded conflicting results. To derive a more precise estimation of this association, we conducted a meta-analysis and systematic review. Methodology/Principal Findings: A comprehensive search was conducted to identify eligible studies of the CCND1 G870A polymorphism and colorectal cancer risk. Pooled odds ratios (ORs) with 95 % confidence intervals (CIs) were derived from a fixed effect or random effect model. We applied a grading system (Venice criteria) that assessed the epidemiological strength...
We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate...
Background: Cyclin D1 protein plays an important part in regulating the progress of the cell during ...
Alternate splicing of the cyclin D1 gene gives rise to transcript a and b which encode two protein i...
BACKGROUND: Cyclin D1 (CCND1) plays a vital role in cancer cell cycle progression. Numerous epidemio...
G870A polymorphism and the risk of colorectal cancer. However, these studies have yielded conflicti...
Colorectal cancer is the third most common cause of cancer and cancer mortality among men and women ...
The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is inc...
Background: The aim of this case-control study was to investigate whether the common G870A polymorph...
The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is inc...
Background: Cyclin D1 (CCND1) plays a key role in cell cycle regulation. It is a well-established hu...
<p>Chi<sub>H</sub><sup>2</sup> and P<sub>H</sub>: chi-squared and P values of the Q-test of heteroge...
Cyclin D1 (CCND1) regulates cellular decision between proliferation and growth arrest. Despite the f...
Cyclin D1 is a key regulatory protein in the progression of G1-S phase of the cell cycle. Activated ...
Ulcerative colitis (UC), a form of inflammatory bowel disease (IBD), is associated with a significan...
We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate...
We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate...
Background: Cyclin D1 protein plays an important part in regulating the progress of the cell during ...
Alternate splicing of the cyclin D1 gene gives rise to transcript a and b which encode two protein i...
BACKGROUND: Cyclin D1 (CCND1) plays a vital role in cancer cell cycle progression. Numerous epidemio...
G870A polymorphism and the risk of colorectal cancer. However, these studies have yielded conflicti...
Colorectal cancer is the third most common cause of cancer and cancer mortality among men and women ...
The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is inc...
Background: The aim of this case-control study was to investigate whether the common G870A polymorph...
The molecular basis for most non-HNPCC familial colorectal cancer cases is unknown, but there is inc...
Background: Cyclin D1 (CCND1) plays a key role in cell cycle regulation. It is a well-established hu...
<p>Chi<sub>H</sub><sup>2</sup> and P<sub>H</sub>: chi-squared and P values of the Q-test of heteroge...
Cyclin D1 (CCND1) regulates cellular decision between proliferation and growth arrest. Despite the f...
Cyclin D1 is a key regulatory protein in the progression of G1-S phase of the cell cycle. Activated ...
Ulcerative colitis (UC), a form of inflammatory bowel disease (IBD), is associated with a significan...
We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate...
We examined the influence that rare variants and low-frequency polymorphisms in the cancer candidate...
Background: Cyclin D1 protein plays an important part in regulating the progress of the cell during ...
Alternate splicing of the cyclin D1 gene gives rise to transcript a and b which encode two protein i...