ORIGINAL PAPER Green synthesis of gold nanoparticles and their anticancer activity

Abstract As the nano revolution unfolds, it is imperative to integrate nanoscience and medicine. The secret gleaned from nature have led to the generation of biogenic technologies for the fabrication of advanced nanomaterials. Present investiga-tion discloses the gold nanoparticles biosynthesizing capabil-ity of the flower of pharmacologically important tree Couroupita guianensis. Rapid, cost-effective, one-step pro-cess of synthesis has been achieved. Newly genre gold nanoparticles were characterized by involving UV–vis spec-troscopy, FTIR, XRD, SEM, and TEM analysis. Interestingly, as a result of extensive screening on the application of newly synthesized gold nanoparticles their anticancer potential has been discovered using MTT assay, DNA fragmentation, apo-ptosis by DAPI staining, and comet assay for DNA damage