Understanding biological complexity demands a combination of high-throughput data and interdisciplinary skills. One way to bring to bear the necessary combination of data types and expertise is by encapsulating domain know-ledge in software and composing that software to create a customized data analysis environment. To this end, simple flexible strategies are needed for interconnecting heterogeneous software tools and enabling data exchange between them. Drawing on our own work and that of others, we present several strategies for interoperability and their consequences, in particular, a set of simple data structuresçlist, matrix, network, table and tupleçthat have proven sufficient to achieve a high degree of interoperability.We provide a...
Biological information computing is rapidly advancing from homogeneous data computation to large-sca...
Researchers in quantitative systems biology make use of a large number of different software package...
Summary: The two main functions of bioinformatics are the organization and analysis of biological da...
Abstract Background In systems biology, and many other areas of research, there is a need for the in...
Researchers in computational biology today make use of a large number of different software packages...
Abstract- ToolBus is an integrated environment in which data and tools can be interoperable in an op...
Bioinformaticians have developed large collections of tools to make sense of the rapidly growing poo...
Although computer programs and database resources for bioinformatics applications are becoming more ...
Present distributed systems consist of loosely coupled fully autonomous databases on which only dist...
Abstract Motivation In the biological sciences, the need to analyse vast amounts of information has ...
Researchers in quantitative systems biology make use of a large number of different software package...
This thesis argues that a ‘minimal computer language’, and a software tool called a ‘generator’, can...
The past twenty years have witnessed an explosion of biological data in diverse database formats gov...
High-throughput experiments generate vast quantities of biological information that are stored in au...
Abstract Background The analysis and usage of biological data is hindered by the spread of informati...
Biological information computing is rapidly advancing from homogeneous data computation to large-sca...
Researchers in quantitative systems biology make use of a large number of different software package...
Summary: The two main functions of bioinformatics are the organization and analysis of biological da...
Abstract Background In systems biology, and many other areas of research, there is a need for the in...
Researchers in computational biology today make use of a large number of different software packages...
Abstract- ToolBus is an integrated environment in which data and tools can be interoperable in an op...
Bioinformaticians have developed large collections of tools to make sense of the rapidly growing poo...
Although computer programs and database resources for bioinformatics applications are becoming more ...
Present distributed systems consist of loosely coupled fully autonomous databases on which only dist...
Abstract Motivation In the biological sciences, the need to analyse vast amounts of information has ...
Researchers in quantitative systems biology make use of a large number of different software package...
This thesis argues that a ‘minimal computer language’, and a software tool called a ‘generator’, can...
The past twenty years have witnessed an explosion of biological data in diverse database formats gov...
High-throughput experiments generate vast quantities of biological information that are stored in au...
Abstract Background The analysis and usage of biological data is hindered by the spread of informati...
Biological information computing is rapidly advancing from homogeneous data computation to large-sca...
Researchers in quantitative systems biology make use of a large number of different software package...
Summary: The two main functions of bioinformatics are the organization and analysis of biological da...