Gastric cancer is among the leading causes of cancer-related deaths worldwide. While heritable forms of gastric cancer are relatively rare, identifying the genes responsible for such cases can inform diagnosis and treatment for both hereditary and sporadic cases of gastric cancer. Mutations in the E-cadherin gene, CDH1, account for 40 % of the most common form of familial gastric cancer (FGC), hereditary diffuse gastric cancer (HDGC). The genes responsible for the remaining forms of FG
Inherited mutations in the E-cadherin gene (CDH1) were described recently in three Maori kindreds wi...
ABSTRACT – Background – Familial aggregation of gastric cancer has pointed out to a possible heredit...
Gastric cancer is a complex disease influenced by strong genetic and environmental factors. Heredita...
BACKGROUND: Most gastric cancer (GC) is sporadic and seem to be mostly related to a cumulative eff...
Importance. Familial aggregation occurs in approximately 10% of gastric cancers, which are generally...
Abstract Approximately 10% of gastric cancer cases show familial clustering but only 1-3% of gastric...
Hereditary diffuse gastric cancer (HDGC) is a recently defined cancer syndrome caused by inactivatin...
Gastric cancer is among the leading causes of cancer-related deaths worldwide. While heritable forms...
Little is known about the relative contributions of genetic and environmental factors to the develop...
Hereditary diffuse gastric cancer (HDGC) is a rare autosomal dominant syndrome associated with an ea...
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically ...
To evaluate the frequency and nature of E-cadherin gene (CDH1) germline mutations in familial gastri...
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically...
Inherited mutations in the E-cadherin gene (CDH1) were described recently in three Maori kindreds wi...
E-cadherin germ-line mutations have recently been described as a molecular basis for early-onset fam...
Inherited mutations in the E-cadherin gene (CDH1) were described recently in three Maori kindreds wi...
ABSTRACT – Background – Familial aggregation of gastric cancer has pointed out to a possible heredit...
Gastric cancer is a complex disease influenced by strong genetic and environmental factors. Heredita...
BACKGROUND: Most gastric cancer (GC) is sporadic and seem to be mostly related to a cumulative eff...
Importance. Familial aggregation occurs in approximately 10% of gastric cancers, which are generally...
Abstract Approximately 10% of gastric cancer cases show familial clustering but only 1-3% of gastric...
Hereditary diffuse gastric cancer (HDGC) is a recently defined cancer syndrome caused by inactivatin...
Gastric cancer is among the leading causes of cancer-related deaths worldwide. While heritable forms...
Little is known about the relative contributions of genetic and environmental factors to the develop...
Hereditary diffuse gastric cancer (HDGC) is a rare autosomal dominant syndrome associated with an ea...
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically ...
To evaluate the frequency and nature of E-cadherin gene (CDH1) germline mutations in familial gastri...
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically...
Inherited mutations in the E-cadherin gene (CDH1) were described recently in three Maori kindreds wi...
E-cadherin germ-line mutations have recently been described as a molecular basis for early-onset fam...
Inherited mutations in the E-cadherin gene (CDH1) were described recently in three Maori kindreds wi...
ABSTRACT – Background – Familial aggregation of gastric cancer has pointed out to a possible heredit...
Gastric cancer is a complex disease influenced by strong genetic and environmental factors. Heredita...