RESEARCH ARTICLE The Ages and Stages Questionnaire and Neurodevelopmental Impairment in Two-

Objective To test the ability of the Ages and Stages Questionnaire, Third Edition (ASQ3) to help iden-tify or exclude neurodevelopmental impairment (NDI) in very preterm-born children at the corrected age of two. Methods We studied the test results of 224 children, born at <32 postmenstrual weeks, who had scores on ASQ3 and Bayley Scales of Infant and Toddler Development, Third Edition (BSI-DIII) and neurological examination at 22–26 months ’ corrected age. We defined NDI as a score of <70 on the cognitive—or motor composite scale of BSIDIII, or impairment on neuro-logical examination or audiovisual screening. We compared NDI with abnormal ASQ3 scores, i.e., <-2SDs on any domain, and with ASQ3 total scores. To correct for possible overestimation of BSIDIII, we also analyzed the adjusted BSIDIII thresholds for NDI, i.e., scores <80 and <85