Clinical Study Outcome of Rhabdomyosarcoma in First Year of Life: Children’s

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background. Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children. Fifty percent of RMS cases occur in the first 10 years of life and less commonly in infants younger than one-year old. These infants require adapted multimodality treatment approaches. Patients andMethods. We analyzed patients ’ characteristics, treatment modalities, and the outcome for RMS infants treated at Children’s Cancer Hospital Egypt (CCHE) between July 2007 and December 2010 and compared them to patients above one year treated on the sameprotocol.Results. Out of the 126RMS treated during this period, 18were below the age of one year. Themale: female ratio was 1.25: 1.Themedian age at diagnosis was 0.7 ± 0.2 years. Most of the cases (27.8%) were presented in head andneck regions.The estimated 4-years failure-free survival and overall survival for infantswere 49 ± 12%and 70 ± 12%, respectively