Total IgA and IgA reactivity to antigen I/II epitopes in HLA- DRB1*04 positive subjects

Bacterial adherence to the acquired dental pellicle, important in dental caries (caries), is mediated by receptor-adhesins such as salivary agglutinin binding to Streptococcus mutans antigen I/II (I/ II). Ten selected I/II epitopes were chosen to determine their reactivity to human salivary IgA. Previous studies suggested that a specific HLA biomarker group (HLA-DRB1*04) may have Copyright © 2013 V. Wallace McCarlie et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use