WORLD JOURNAL OF SURGICAL ONCOLOGY

Full list of author information is available at the end of the articlecancers. There are several known prognostic factors for patients with NSCLC. The most important prognostic factor for NSCLC is tumor stage, with advanced stage disease being associated with the poorest prognosis. Sev-eral studies have shown the relationship of pretreatment stages of various malignancies and many experimental and clinical studies have been performed to explain this phenomenon. However, the mechanism of thrombocytosis in patients with cancer is not yet fully understood. It re-mains unclear whether thrombocytosis is the final result of advanced malignancies or the direct cause that in-creases the risk of recurrence and metastasis. This study was designed to evaluate the prognostic value of preopera-tive thrombocytosis in patients with NSCLC who undergo surgery