Add to ORKGAbstract: The rising tide of obesity and its related disorders is one of the most pressing health concerns worldwide, yet existing medicines to combat the problem are disappointingly limited in number and effectiveness. Recent advances in mechanistic insights into the neuroendocrine regulation of body weight have revealed an expanding list of molecular tar-gets for novel, rationally designed antiobesity pharmaceutical agents. Antiobesity drugs act via any of four mechanisms: 1) decreasing energy intake, 2) increasing energy expenditure or modulating lipid metabolism, 3) modulating fat stores or adipocyte differentiation, and 4) mimicking caloric restriction. Various novel drug candidates and targets directed against obesity are currently be...
Aims: Obesity and its main metabolic complication, type 2 diabetes, have attained the status of a gl...
Obesity is an increasingly serious socioeconomic and clinical problem. Between 1/4 - 1/3 of populati...
Obesity is a multifactorial, chronic disorder that has reached epidemic proportions in most industri...
Obesity is pandemic and a multidisciplinary approach is critical for its management. Anti-obesity tr...
The pharmacotherapy of obesity has historically recorded an overall poor safety and efficacy profile...
Obesity is a global epidemic that contributes to a number of health complications including cardiova...
[[abstract]]The prevalence of obesity has rapidly increased in all industrialized countries in the p...
Obesity will continue to be one of the leading causes of chronic disease unless the ongoing rise in ...
The Author(s) 2015. This article is published with open access at Springerlink.com Abstract There is...
After many years of research, obesity is still a disease with an unmet medical need. Very few compou...
The growing worldwide prevalence of obesity needs urgent attention because the potential morbidity, ...
Nonpharmacological approach to the prevention and treatment of obesity includes considerable lifesty...
Abstract: Obesity is a serious socioeconomic, and also increasingly clinical problem. Between �- 1 /...
“Disease will always be with us, but we may look forward confidently to a time when epidemics shall ...
Several pharmacological approaches to controlling body weight have been developed over the last deca...
Aims: Obesity and its main metabolic complication, type 2 diabetes, have attained the status of a gl...
Obesity is an increasingly serious socioeconomic and clinical problem. Between 1/4 - 1/3 of populati...
Obesity is a multifactorial, chronic disorder that has reached epidemic proportions in most industri...
Obesity is pandemic and a multidisciplinary approach is critical for its management. Anti-obesity tr...
The pharmacotherapy of obesity has historically recorded an overall poor safety and efficacy profile...
Obesity is a global epidemic that contributes to a number of health complications including cardiova...
[[abstract]]The prevalence of obesity has rapidly increased in all industrialized countries in the p...
Obesity will continue to be one of the leading causes of chronic disease unless the ongoing rise in ...
The Author(s) 2015. This article is published with open access at Springerlink.com Abstract There is...
After many years of research, obesity is still a disease with an unmet medical need. Very few compou...
The growing worldwide prevalence of obesity needs urgent attention because the potential morbidity, ...
Nonpharmacological approach to the prevention and treatment of obesity includes considerable lifesty...
Abstract: Obesity is a serious socioeconomic, and also increasingly clinical problem. Between �- 1 /...
“Disease will always be with us, but we may look forward confidently to a time when epidemics shall ...
Several pharmacological approaches to controlling body weight have been developed over the last deca...
Aims: Obesity and its main metabolic complication, type 2 diabetes, have attained the status of a gl...
Obesity is an increasingly serious socioeconomic and clinical problem. Between 1/4 - 1/3 of populati...
Obesity is a multifactorial, chronic disorder that has reached epidemic proportions in most industri...