RESEARCH ARTICLE Characterisation of inflam coagulation, and radiolog o

Full list of author information is available at the end of the articleBackground Schistosomiasis is a debilitating chronic infection caused by trematode worms of the genus Schistosoma. Rural re-gions in the tropics are most affected leading to a global disease burden of 3–70 million disability-adjusted life years lost [1]. Humans become infected during freshwater exposure by larval stages of Schistosoma spp. (cercariae) shed from the snail intermediate host. Cercariae penetrate the intact skin, migrate to and evolve in the venous drain-age systems of several tissues in the human host, including the urogenital tract (S. haematobium) and the intestines (S. mansoni, intercalatum, japonicum, mekongi). The pres-ence of adult worms and their eggs in human tissues ul-timately lead to a variety of chronic pathologies including haematuria, haematochaezia, liver fibrosis, bladder cancer, and chronic inflammation of the urogenital tract [2]. Katayama fever is an acute inflammatory syndrome resul