Research Article Comparison of Hippocampal Volume in Dementia Subtypes

Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Aims. To examine the relationship between different types of dementia and hippocampal volume.Methods. Hippocampal volume was measured using FL3D sequence magnetic resonance imaging in 26 Alzheimer’s, vascular dementia, mixed dementia, and normal pressure hydrocephalus patients and 15 healthy controls and also hippocampal ratio, analyzed. Minimental scale was used to stratify patients on cognitive function impairments. Results. Hippocampal volume and ratio was reduced by 25 % in Alzheimer’s disease, 21 % in mixed dementia, 11 % in vascular dementia and 5 % in normal pressure hydrocephalus in comparison to control. Also an asymmetrical decrease in volume of le hippocampus was noted. e severity of dementia increased in accordance to decreasing hippocampal volume. Conclusion. Measurement in hippocampal volume may facilitate in differentiating different types of dementia and in disease progression.erewas a correlation between hippocampal volume and severity of cognitive impairment. 1