The second issue of Molecular Biotechnology offers us a variety of interesting topics ranging from basic science to industrial applications. The current strength of the field and this new journal come into conjunction when we verify how close new genomic tools and commonly used prod-ucts really are. Indeed, it would not be outrageous to say that we can taste the flavours and sense the aroma of microbial biotechnology while cheering for systems biology. This new issue opens with a wonderfully tasting review entitled ‘Wine genomics ’ (Siezen, 2008) who takes us from grape diversity to wine bacteria and yeast genomics. The article is a real overview on winemaking in which ancient traditions and modern systems biology walk hand in hand. It migh...