Add to ORKGIntroduction: Genes involved in testicular differentiation, spermatogenesis, proliferation and apoptosis of germ cells have been shown to evolve rapidly and display rapid DNA changes. These genes are therefore good candidates for explaining impairments in spermatogenesis. Initial studies of some of these genes appear to confirm this hypothesis. The RHOXF2 candidate gene belongs to the RHOX family clustered in Xq24 and is specifically expressed in the testis. It contains four exons and codes for a 288 amino acid (aa) transcription factor. It has a high degree o
International audienceThe reproductive homeobox on the X chromosome (RHOX) genes were first identifi...
Copyright © 2010 Paulo Navarro-Costa et al. This is an open access article distributed under the Cre...
Two percent of human males are infertile because of severe defects in sperm production. In the clini...
The X-linked reproductive homeobox (RHOX) gene cluster encodes transcription factors preferentially ...
The X-linked reproductive homeobox (RHOX) gene cluster encodes transcription factors preferentially ...
Secretory azoospermia is a severe form of male infertility caused by unknown factors. DAX-1 is predo...
Background It was believed earlier that spermatozoa have no traces of RNA because of loss of most of...
The molecular basis of spermatogenic failure (SpF) is still largely unknown. Accumulating evidence s...
Homeobox proteins are transcription factors that play key roles in the process of embryogenesis. Her...
Infertility is a widespread health problem, caused by the male factor in about half of all cases, an...
Speciation, the formation of new species, is an essential evolutionary process that causes species d...
Speciation, the formation of new species, is an essential evolutionary process that causes species d...
RNA interference (RNAi) is widely used to determine the function of genes. We chose this approach to...
Rhox8 ablation in the Sertoli cells using a tissue-specific RNAi approach results in impaired male f...
Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen...
International audienceThe reproductive homeobox on the X chromosome (RHOX) genes were first identifi...
Copyright © 2010 Paulo Navarro-Costa et al. This is an open access article distributed under the Cre...
Two percent of human males are infertile because of severe defects in sperm production. In the clini...
The X-linked reproductive homeobox (RHOX) gene cluster encodes transcription factors preferentially ...
The X-linked reproductive homeobox (RHOX) gene cluster encodes transcription factors preferentially ...
Secretory azoospermia is a severe form of male infertility caused by unknown factors. DAX-1 is predo...
Background It was believed earlier that spermatozoa have no traces of RNA because of loss of most of...
The molecular basis of spermatogenic failure (SpF) is still largely unknown. Accumulating evidence s...
Homeobox proteins are transcription factors that play key roles in the process of embryogenesis. Her...
Infertility is a widespread health problem, caused by the male factor in about half of all cases, an...
Speciation, the formation of new species, is an essential evolutionary process that causes species d...
Speciation, the formation of new species, is an essential evolutionary process that causes species d...
RNA interference (RNAi) is widely used to determine the function of genes. We chose this approach to...
Rhox8 ablation in the Sertoli cells using a tissue-specific RNAi approach results in impaired male f...
Polymorphisms in cell death pathway genes are associated with altered sperm apoptosis and poor semen...
International audienceThe reproductive homeobox on the X chromosome (RHOX) genes were first identifi...
Copyright © 2010 Paulo Navarro-Costa et al. This is an open access article distributed under the Cre...
Two percent of human males are infertile because of severe defects in sperm production. In the clini...