Copyright © 2013 Andrew S. Sage et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Sigma receptor antagonists diminish the effects of cocaine in behavioral assays, including conditioned place preference. Previous locomotor activity experiments in mice determined that the sigma receptor ligand YZ-185 (N-phenylpropyl-N-(3-methoxyphen-ethyl)piperazine) enhanced cocaine-induced hyperactivity at a lower (0.
Sigma receptors (σ-1 and σ-2) are non-opioid proteins implicated in the pathophysiology of various n...
The discovery and evaluation of high affinity dopamine transport inhibitors with low abuse liability...
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appe...
Title from PDF of title page (University of Missouri--Columbia, viewed on October 25, 2010).The enti...
Cocaine is a highly abused drug without effective pharmaco-therapies to treat it. It interacts with ...
Cocaine is a powerful psychostimulant that is highly abused by 1.9 million people in the United Stat...
Sigma receptors have been well documented as a protein target for cocaine and have been shown to be ...
Drug addiction is a chronic, debilitating disease that affects millions of people around the world c...
Methamphetamine is an addictive psychostimulant drug with an increasing prevalence of abuse worldwid...
Cocaine is a psychotropic drug with a high potential for abuse due to its euphoric effects. Efforts ...
Sigma receptor (R) antagonists attenuate many behavioral ef-fects of cocaine but typically not its r...
There are currently no well characterized sigma functional assays. Until such an assay is developed,...
Although sigma receptors were discovered in 1982, the biochemical and physiological roles of sigma r...
Sigma (\u3c3) receptors are involved in several functions such as modulation and biosynthesis of sev...
The histaminergic system has been speculated to be involved in the inhibitory control of drug reward...
Sigma receptors (σ-1 and σ-2) are non-opioid proteins implicated in the pathophysiology of various n...
The discovery and evaluation of high affinity dopamine transport inhibitors with low abuse liability...
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appe...
Title from PDF of title page (University of Missouri--Columbia, viewed on October 25, 2010).The enti...
Cocaine is a highly abused drug without effective pharmaco-therapies to treat it. It interacts with ...
Cocaine is a powerful psychostimulant that is highly abused by 1.9 million people in the United Stat...
Sigma receptors have been well documented as a protein target for cocaine and have been shown to be ...
Drug addiction is a chronic, debilitating disease that affects millions of people around the world c...
Methamphetamine is an addictive psychostimulant drug with an increasing prevalence of abuse worldwid...
Cocaine is a psychotropic drug with a high potential for abuse due to its euphoric effects. Efforts ...
Sigma receptor (R) antagonists attenuate many behavioral ef-fects of cocaine but typically not its r...
There are currently no well characterized sigma functional assays. Until such an assay is developed,...
Although sigma receptors were discovered in 1982, the biochemical and physiological roles of sigma r...
Sigma (\u3c3) receptors are involved in several functions such as modulation and biosynthesis of sev...
The histaminergic system has been speculated to be involved in the inhibitory control of drug reward...
Sigma receptors (σ-1 and σ-2) are non-opioid proteins implicated in the pathophysiology of various n...
The discovery and evaluation of high affinity dopamine transport inhibitors with low abuse liability...
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appe...