Post-reperfusion Syndrome during Renal Transplantation: A Retrospective Study

licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. Received: 2012.04.13; Accepted: 2012.07.09; Published: 2012.07.16 Post-reperfusion syndrome (PRS) is a serious, widely reported complication following the reperfusion of an ischemic tissue or organ. We sought to determine the prevalence, risk factors and short-term outcomes of PRS related renal transplantation. We conducted a retrospective, case-control study of patients undergoing renal transplantation between July 2006 and March 2008. Identification of PRS was based on a drop in mean arterial pressure by at least 15 % within 5 minutes of donor kidney reperfusion. Of the 150 consecutive renal transplantations reviewed, 6 patients (4%) met criteria for post-reperfusion syndrome. Univariate analysis showed that an age over 60, diabetes mellitus, Asian race, and extended criteria donors increased the odds of developing PRS by 4.8 times (95 % CI [1.2, 20]; P=.0338), 4.5 times (95 % CI [1.11, 18.8]; P=.0378), 35.5 times (95 % CI [3.94, 319.8]; P=0.0078) and 9.6 times (95 % CI [1.19, 76.28] P=0.0115) respectively. Short term follow-up revealed increased graft failure rate within 6 months (6 % vs. 16 % P=0.0125) and almost twice the number o