Visceral pain is a global term used to describe pain originating from the internal organs, which is distinct from somatic pain. It is a hallmark of functional gastrointestinal disorders such as irritable-bowel syndrome (IBS). Currently, the treatment strategies targeting vis-ceral pain are unsatisfactory, with development of novel therapeutics hindered by a lack of detailed knowledge of the underlying mechanisms. Stress has long been implicated in the pathophysiology of visceral pain in both preclinical and clinical studies. Here, we discuss the complex etiology of visceral pain reviewing our current understanding in the context of the role of stress, gender, gut microbiota alterations, and immune functioning. Furthermore, we review the rol...
Women have a higher incidence of various visceral and neuropathic chronic pain conditions. Most of t...
Gastrointestinal disorders with abdominal pain are associated with central sensitization and psychop...
Structural brain alterations in chronic pain conditions remain incompletely understood, especially i...
Visceral pain is generally poorly localized and characterized by hypersensitivity to a stimulus such...
Visceral pain is a debilitating disorder which affects up to 25% of the population at any one time. ...
Visceral pain is a debilitating symptom of irritable bowel syndrome (IBS), a disorder affecting up t...
Stressors of different psychological, physical or immune origin play a critical role in the pathophy...
Visceral hypersensitivity of the lower gastrointestinal tract, defined as an increased response to c...
Visceral pain, a debilitating hallmark of disorders of gut-brain axis interactions such as irritable...
Temporomandibular disorder (TMD) and irritable bowel syndrome (IBS) are 2 chronic overlapping pain c...
A growing body of preclinical and clinical evidence supports a relationship between the complexity a...
AbstractTemporomandibular disorder and irritable bowel syndrome are comorbid functional chronic pain...
Gastrointestinal (GI) discomfort is a hallmark of most gut disorders and represents an important com...
Abdominal pain is one of the most difficult to treat symptoms in patients suffering from Functional ...
Irritable bowel syndrome (IBS) is a common functional gastro-intestinal disorder, characterized by a...
Women have a higher incidence of various visceral and neuropathic chronic pain conditions. Most of t...
Gastrointestinal disorders with abdominal pain are associated with central sensitization and psychop...
Structural brain alterations in chronic pain conditions remain incompletely understood, especially i...
Visceral pain is generally poorly localized and characterized by hypersensitivity to a stimulus such...
Visceral pain is a debilitating disorder which affects up to 25% of the population at any one time. ...
Visceral pain is a debilitating symptom of irritable bowel syndrome (IBS), a disorder affecting up t...
Stressors of different psychological, physical or immune origin play a critical role in the pathophy...
Visceral hypersensitivity of the lower gastrointestinal tract, defined as an increased response to c...
Visceral pain, a debilitating hallmark of disorders of gut-brain axis interactions such as irritable...
Temporomandibular disorder (TMD) and irritable bowel syndrome (IBS) are 2 chronic overlapping pain c...
A growing body of preclinical and clinical evidence supports a relationship between the complexity a...
AbstractTemporomandibular disorder and irritable bowel syndrome are comorbid functional chronic pain...
Gastrointestinal (GI) discomfort is a hallmark of most gut disorders and represents an important com...
Abdominal pain is one of the most difficult to treat symptoms in patients suffering from Functional ...
Irritable bowel syndrome (IBS) is a common functional gastro-intestinal disorder, characterized by a...
Women have a higher incidence of various visceral and neuropathic chronic pain conditions. Most of t...
Gastrointestinal disorders with abdominal pain are associated with central sensitization and psychop...
Structural brain alterations in chronic pain conditions remain incompletely understood, especially i...