Cryptococcus neoformans is a ubiquitous human fungal pathogen that causes meningoencephalitis in predominantly immunocompromised hosts. The fungus is typically haploid, and sexual reproduction involves two individuals with opposite mating types/sexes, a and a. However, the overwhelming predominance of mating type (MAT) a over a in C. neoformans populations limits a–a mating in nature. Recently it was discovered that C. neoformans can undergo same-sex mating under laboratory conditions, especially between a isolates. Whether same-sex mating occurs in nature and contributes to the current population structure was unknown. In this study, natural aADa hybrids that arose by fusion between two a cells of different serotypes (A and D) were identif...
<div><p>Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes....
Recent attempts to characterise the hybrid strains of Cryptococcus neoformans have led to the identi...
<p>Sexual reproduction in fungi is governed by a specialized genomic region called the mating-type l...
Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer ...
The most common cause of fungal meningitis in humans, Cryptococcus neoformans serotype A, is a basid...
The sexual mating of the pathogenic yeast Cryptococcus neoformans is important for pathogenesis stud...
Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer ...
The recent efforts to characterize the hybrid strains of Cryptococcus neoformans has led to the iden...
<div><p>Aneuploidy is known to be deleterious and underlies several common human diseases, including...
Sexual reproduction in fungi is governed by a specialized genomic region called the mating-type locu...
Cryptococcus gattii is a basidiomycetous human fungal pathogen that typically causes infection in tr...
Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes. Fungi e...
Courtship is pivotal for successful mating. However, courtship is challenging for the Cryptococcus n...
<div><p>Sexual reproduction in fungi is governed by a specialized genomic region called the mating-t...
International audienceNatural hybridization between two strains, varieties, or species is a common p...
<div><p>Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes....
Recent attempts to characterise the hybrid strains of Cryptococcus neoformans have led to the identi...
<p>Sexual reproduction in fungi is governed by a specialized genomic region called the mating-type l...
Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer ...
The most common cause of fungal meningitis in humans, Cryptococcus neoformans serotype A, is a basid...
The sexual mating of the pathogenic yeast Cryptococcus neoformans is important for pathogenesis stud...
Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer ...
The recent efforts to characterize the hybrid strains of Cryptococcus neoformans has led to the iden...
<div><p>Aneuploidy is known to be deleterious and underlies several common human diseases, including...
Sexual reproduction in fungi is governed by a specialized genomic region called the mating-type locu...
Cryptococcus gattii is a basidiomycetous human fungal pathogen that typically causes infection in tr...
Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes. Fungi e...
Courtship is pivotal for successful mating. However, courtship is challenging for the Cryptococcus n...
<div><p>Sexual reproduction in fungi is governed by a specialized genomic region called the mating-t...
International audienceNatural hybridization between two strains, varieties, or species is a common p...
<div><p>Sexual reproduction is a universal mechanism for generating genetic diversity in eukaryotes....
Recent attempts to characterise the hybrid strains of Cryptococcus neoformans have led to the identi...
<p>Sexual reproduction in fungi is governed by a specialized genomic region called the mating-type l...