MEETING ABSTRACT Open Access Hemodynamically significant ductus arteriosus: a new targeted approach

Debate on hemodynamically significant ductusarteriosus (hsDA) in premature infants remains unresolved. The association between patent ductus arteriosus (PDA) and the most adverse outcomes and comorbid-ities in preterms (peri-intraventricular haemorrhage, necrotizing enterocolitis, chronic lung disease, pulmon-ary haemorrhage and mortality) has led to the integra-tion of ductal closure into neonatal intensive care. The recent theory that describes PDA as “an innocent bystander ” is supported by the lack of evidence of signif-icant benefits on long-term outcomes with therapeutic interventions. So, the causal relationship between PDA and comorbidities is questioned. Moreover, PDA can close spontaneously in a significant proportion of pre-terms [1]