A Systematic Review and Meta-Analysis

Copyright © 2013 Pei-Xin Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Studies have reported inconsistent results regarding clinical feature and the prognosis status of the affected children in China melamine-contamination event. We summarized available literatures by performing a review and meta-analysis.Methods. Statistical pooling was performed using random-effects model; the sources of heterogeneity were explored through subgroup analyses. Results. Twenty-six studies involving 2164 patients with kidney abnormalities were identified; 94.4 % of the patients had urinary calculi and 95.8 % of the calculi were <10mm in diameter. Of 2040 patients with known types of treatment, 5.6 % underwen