Retinal Blood Vessel Distribution Correlates With the Peripapillary Retinal Nerve Fiber Layer Thickness Profile as Measured With GDx VCC and ECC

Purpose: Aim of the present study was to evaluate whether there is a correlation between retinal blood vessel density (RVD) and the peripapillary retinal nerve fiber layer (RNFL) thickness profile. Methods: RNFL thickness of 106 healthy subjects was measured using scanning laser polarimetry, GDx variable corneal compen-sation (VCC), and GDx enhanced corneal compensation (ECC). A proprietary software was developed in MATLAB to measure the peripapillary retinal vessels using scanning laser ophthalmoscopy fundus images, centered on the optic disc measured by Cirrus spectral domain optical coherence tomography. The individual retinal vessel positions and thickness values were integrated in a 64-sector RVD profile and intrasubject and intersubject correlations were calculated. Results: The mean R value±SD for intrasubject correlation between RVD and RNFL thickness measured with GDx VCC an