Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells Shien Hu1, Lan Liu2, Eugene B. Chang3, Jian-Ying Wang2 and Jean-Pierre Raufman1* Background: Compromised colonic butyrate production resulting from low dietary fiber or altered gut microbiota may promote colon neoplasia. Previous reports indicate these actions are mediated in part by altered levels of miRNAs, including suppressed expression of the oncogenic miR-17-92a cluster. Here, we sought to identify the mechanisms underlying these effects of butyrate in colon cancer. Methods: miR-92a levels were measured in archived human colon cancer and adjacent normal colon specimens by microarray and quantitative RT-...
he short chain fatty acid (SCFA) butyrate, a product of fermentation of dietary fiber in the human c...
Gene-environment interactions are so numerous and biologically complicated that it can be challengin...
The prohibitory effects of dietary fiber in colorectal cancer have been identified, although the det...
Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short chain f...
Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short chain f...
Background: As the end product of the bacterial fermentation of dietary fiber in the colonic lumen, ...
Butyrate, an intestinal microbiota metabolite of dietary fiber, exhibits chemoprevention effects on ...
The intestinal microbiota is well known to have multiple benefits on human health, including cancer ...
The intestinal microbiota is well known to have multiple benefits on human health, including cancer ...
AbstractInhibition of the enzyme histone deacetylase by butyrate results in the direct transcription...
PURPOSE: The gut fermentation product of dietary fiber, butyrate, inhibits growth of HT29, an establ...
ABSTRACT Whether dietary fi ber protects against colorectal cancer is controversial because of confl...
aBstRact Whether dietary fiber protects against colorectal cancer is controversial because of confli...
Butyrate is a short-chain fatty acid decomposed from dietary fiber and has been shown to have effect...
AbstractA wealth of evidence correlates the chemopreventive activity of a fiber-rich diet with the p...
he short chain fatty acid (SCFA) butyrate, a product of fermentation of dietary fiber in the human c...
Gene-environment interactions are so numerous and biologically complicated that it can be challengin...
The prohibitory effects of dietary fiber in colorectal cancer have been identified, although the det...
Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short chain f...
Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short chain f...
Background: As the end product of the bacterial fermentation of dietary fiber in the colonic lumen, ...
Butyrate, an intestinal microbiota metabolite of dietary fiber, exhibits chemoprevention effects on ...
The intestinal microbiota is well known to have multiple benefits on human health, including cancer ...
The intestinal microbiota is well known to have multiple benefits on human health, including cancer ...
AbstractInhibition of the enzyme histone deacetylase by butyrate results in the direct transcription...
PURPOSE: The gut fermentation product of dietary fiber, butyrate, inhibits growth of HT29, an establ...
ABSTRACT Whether dietary fi ber protects against colorectal cancer is controversial because of confl...
aBstRact Whether dietary fiber protects against colorectal cancer is controversial because of confli...
Butyrate is a short-chain fatty acid decomposed from dietary fiber and has been shown to have effect...
AbstractA wealth of evidence correlates the chemopreventive activity of a fiber-rich diet with the p...
he short chain fatty acid (SCFA) butyrate, a product of fermentation of dietary fiber in the human c...
Gene-environment interactions are so numerous and biologically complicated that it can be challengin...
The prohibitory effects of dietary fiber in colorectal cancer have been identified, although the det...