PEDIATRIC HYPERTENSION (JT FLYNN, SECTION EDITOR) Treatment Strategies to Prevent Renal Damage

# The Author(s) 2014. This article is published with open access at Springerlink.com Abstract Hypertension secondary to chronic kidney disease prevails in earlier childhood and obesity-related primary hyper-tension in adolescence. Both are associated with a high risk of renal and cardiovascular morbidity. In children with chronic kidney disease, uncontrolled hypertension may accelerate pro-gression to end-stage renal disease before adulthood is reached and increase a child’s risk of cardiac death a thousand-fold. Obesity-related hypertension is a slow and silent killer, and though early markers of renal damage are recognized during childhood, end-stage renal disease is a risk in later life. Renal damage will be a formidable multiplier of cardiovascular risk for adults in whom obesity and hypertension tracks from childhood. Management options to prevent renal damage will vary for these different target groups. This review provides a summary of the available renoprotective strategies in order to aid physicians involved in the care of this challenging group of children