RESEARCH ARTICLE Acceptability and Willingness-to-Pay for a Hypothetical Ebola Virus Vaccine in Nigeria

Background Ebola virus disease is a highly virulent and transmissible disease. The largest recorded fatality from Ebola virus disease epidemic is ongoing in a few countries in West Africa, and this poses a health risk to the entire population of the world because arresting the transmis-sion has been challenging. Vaccination is considered a key intervention that is capable of arresting further spread of the disease and preventing future outbreak. However, no vaccine has yet been approved for public use, although various recombinant vaccines are undergo-ing trials and approval for public use is imminent. Therefore, this study aimed to determine the acceptability of and willingness-to-pay for Ebola virus vaccine by the public. Methods The study was a community-based cross-sectional qualitative and quantitative interven-tional study conducted in two communities, each in two states in Nigeria. An interviewer-administered questionnaire was used to collect information on respondents ’ knowledge of the Ebola virus, the ways to prevent the disease, and their preventive practices, as well a