Add to ORKGABSTRACT Hydrogen peroxide is a key mediator of oxidative stress known to be important in various cellular processes, including apoptosis. B-cell lymphoma-2 (Bcl-2) is an oxidative stress–responsive protein and a key regulator of apoptosis; however, the underlying mecha-nisms of oxidative regulation of Bcl-2 are not well understood. The present study investigates the direct effect of H2O2 on Bcl-2 cysteine oxidation as a potential mechanism of apoptosis regulation. Exposure of human lung epithelial cells to H2O2 induces apoptosis concomitan
International audienceBcl-2 is an anti-apoptotic molecule preventing oxidative stress damage and cel...
SIGNIFICANCE B cell lymphoma-2 (Bcl-2) is the prototypical anti-apoptotic member of the Bcl-2 family...
Thymocytes undergo negative and positive selection during their development in the thymus. During th...
ABSTRACT Hydrogen peroxide is a key mediator of oxidative stress known to be important in various ce...
Exposure of cells to hydrogen peroxide can cause oxidative damage to cellular constituents including...
Hydrogen peroxide (H2O2), a representative ROS, has been used to study the apoptosis of cancer cells...
The role of oxidative stress and apoptosis has recently been recognized as an important determinant ...
AbstractIt has clearly been established that oxidative stress leads to perturbation of various cellu...
Bcl-2 is an antiapoptotic molecule that prevents oxidative stress damage and cell death. We investig...
Treatment with 0.2mM hydrogen peroxide (H2O2) or with 0.5mM cisplatin caused caspase-9 and caspase-3...
Hydrogen peroxide (H2O2) is a compound involved in some mammalian reactions and processes. It modula...
AbstractThe induction of apoptosis in Jurkat T-lymphocytes with 50 μM hydrogen peroxide was associat...
AbstractBcl-2 antagonizes apoptosis through mechanisms which are not completely understood. We have ...
Fetal alveolar type II (fATII) epithelial cells were used to evaluate the role of signaling factors ...
Although the anti-apoptotic effect of Bcl-2 is well established, the role of Bcl-2 in tumour respons...
International audienceBcl-2 is an anti-apoptotic molecule preventing oxidative stress damage and cel...
SIGNIFICANCE B cell lymphoma-2 (Bcl-2) is the prototypical anti-apoptotic member of the Bcl-2 family...
Thymocytes undergo negative and positive selection during their development in the thymus. During th...
ABSTRACT Hydrogen peroxide is a key mediator of oxidative stress known to be important in various ce...
Exposure of cells to hydrogen peroxide can cause oxidative damage to cellular constituents including...
Hydrogen peroxide (H2O2), a representative ROS, has been used to study the apoptosis of cancer cells...
The role of oxidative stress and apoptosis has recently been recognized as an important determinant ...
AbstractIt has clearly been established that oxidative stress leads to perturbation of various cellu...
Bcl-2 is an antiapoptotic molecule that prevents oxidative stress damage and cell death. We investig...
Treatment with 0.2mM hydrogen peroxide (H2O2) or with 0.5mM cisplatin caused caspase-9 and caspase-3...
Hydrogen peroxide (H2O2) is a compound involved in some mammalian reactions and processes. It modula...
AbstractThe induction of apoptosis in Jurkat T-lymphocytes with 50 μM hydrogen peroxide was associat...
AbstractBcl-2 antagonizes apoptosis through mechanisms which are not completely understood. We have ...
Fetal alveolar type II (fATII) epithelial cells were used to evaluate the role of signaling factors ...
Although the anti-apoptotic effect of Bcl-2 is well established, the role of Bcl-2 in tumour respons...
International audienceBcl-2 is an anti-apoptotic molecule preventing oxidative stress damage and cel...
SIGNIFICANCE B cell lymphoma-2 (Bcl-2) is the prototypical anti-apoptotic member of the Bcl-2 family...
Thymocytes undergo negative and positive selection during their development in the thymus. During th...